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Dual Antiplatelet – Appropriate Prescribing

CQC Areas

  • Safe (Medicines Optimisation)
  • Effective (Delivering Evidenced Based Care)
  • Well-led (Learning, Improvement & Innovation)
  • Well-led (Environmental Sustainability)

The benefits of this project

Project benefits for Your Patients

Benefits for Your Patients

  • Less medication to take
  • Fewer side effects
  • Lower bleeding risk
Project benefits for Your Practice

Benefits for Your Practice

  • Fewer side effects so may decrease need for GP appointments
  • Financial savings from reduced medicines spend
Project benefits for The Planet

Benefits for The Planet

  • Reduced prescribing means lower environmental impact

Opportunity for improvement

  • This project aims to help practices prescribe dual antiplatelet therapy appropriately for patients(see disclaimers).  This is key for several reasons:   
  • Reduce side effects and bleeding risk  
  • NICE guidelines advise that dual antiplatelet therapy (DAPT) is usually continued for 12 months following acute coronary syndrome or 6 months following PCI for stable coronary artery disease. If DAPT is continued beyond the recommended course, the bleeding risk may outweigh the benefits.  
  • Reduce inappropriate polypharmacy 
  • There is evidence to suggest that between one third and a half of medication prescribed for long term conditions are not taken as recommended. There is also significant morbidity associated with inappropriate polypharmacy and adverse effects of medication causes an estimated 11% of unplanned hospital admission
  • Reduce carbon footprint from inappropriate polypharmacy 
  • Medicines and chemicals account for 20% of the NHS total carbon footprint and this proportion is significantly higher within primary care
  • You might like to make a SMART goal for this project, e.g. within the next 6 months, ensure 100% of patients prescribed DAPT have a documented review date aligned with NICE guidelines in their records, with a system alert for timely deprescribing.

How to carry out this project

  1. Identify patients

    Run a search for patients prescribed dual antiplatelet therapy (two of either aspirin, clopidogrel, ticagrelor or prasugrel) within the last 6 months. Identify patients whose prescription has continued beyond the intended course length (as per NICE guidance/the timeframe recommended by secondary care). 

    We hope to provide downloadable IT searches for EMIS & System 1 soon.  In the meantime, you could use our EMIS and SystmOne search guides to create your own. 

  2. Discussion & Training

    Run a training session for clinicians on dual antiplatelet appropriate prescribing. Discuss the search findings and how to improve DAPT prescribing

    The practice may like to develop a Standard Operating Procedure (SOP) for DAPT prescriptionsThis could include a system to ensure there is an end date included in the directions of the antiplatelet prescription due to be stopped, visible to both patient and clinician, and consideration of PPI discontinuation at the same time.  

     

  3. Communicate with local pharmacies

    You might like to involve your local community pharmacists so they are aware of the recommendations and can support with consistent messaging to patients.  Your practice pharmacist will likely know how best to get in touch with them.   

  4. Review

    Contact the patients identified to discuss discontinuation.  

    If the lack of clarity exists about the course length, contact secondary care team (usually cardiology) via Advice and Guidance Service. 

  5. Record

    Record the number and type of medications stopped.  

  6. Study

    Review the results, summarise learning, share with practice team + decide if any changes are needed to improve the process. Decide when to re-audit again to ensure the change has lasted e.g. 2-3 months and use the Project Monitoring form to keep track.

    Many practices run automatic searches at regular intervals – speak to your practice team about including this project in those searches. 

How to scale this project up or down

Please note - Use of this project requires NetworkPLUS membership. If you would like to share this project with others, please invite them to purchase their own membership—access must not be shared with non-members.

Your wider organisation e.g. PCN, Cluster, ICB or Healthboard might like to implement this project across their practices to spread its reach.   

You could work with local pharmacy and hospital teams to ensure consistent messaging about DAPT in medicines formularies and that the length of treatment is always included in the discharge summary.  

Case study

“This was a relatively straightforward project which I was able to complete during a 6-month rotation as a GP trainee in ST2. Although the overall numbers of medications stopped are fairly small, the individual impact for patients is significant due to the reduced bleeding risk. There is an overall cost and carbon saving.  

Making phone calls to patients individually took some time, however an alternative approach would be to use text messages alone. 

On an individual level, this project enabled me to gain an insight into deprescribing through a small and focussed project.” 

GP trainee 

East Trees Health Centre, Bristol

Have you completed this QIP?

Tell us a little about your project and enter your data in order to generate a certificate showing the probable cost and carbon savings and other benefits. This project may help with CQC evidence submission (see disclaimers). 

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